Frequent downregulation of 14-3-3 σ protein and hypermethylation of 14-3-3 σ gene in salivary gland adenoid cystic carcinoma
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چکیده
منابع مشابه
Stratifin (14-3-3 σ) Limits Plakophilin-3 Exchange with the Desmosomal Plaque
Desmosomes are prominent cell-cell adhesive junctions in stratified squamous epithelia and disruption of desmosomal adhesion has been shown to have dramatic effects on the function and integrity of these tissues. During normal physiologic processes, such as tissue development and wound healing, intercellular adhesion must be modified locally to allow coordinated cell movements. The mechanisms t...
متن کاملCorrection for “ 14 - 3 - 3 σ regulates B - cell homeostasis through stabilization of FOXO 1
IMMUNOLOGY Correction for “14-3-3σ regulates B-cell homeostasis through stabilization of FOXO1,” by Yu-Wen Su, Zhenyue Hao, Atsushi Hirao, Kazuo Yamamoto, Wen-Jye Lin, Ashley Young, Gordon S. Duncan, Hiroki Yoshida, Andrew Wakeham, Philipp A. Lang, Kiichi Murakami, Pamela Ohashi, and Tak W. Mak, which appeared in issue 4, January 25, 2011, of Proc Natl Acad Sci USA (108:1555–1560; first publish...
متن کاملCorrection for “ 14 - 3 - 3 σ regulates B - cell homeostasis through
IMMUNOLOGY Correction for “14-3-3σ regulates B-cell homeostasis through stabilization of FOXO1,” by Yu-Wen Su, Zhenyue Hao, Atsushi Hirao, Kazuo Yamamoto, Wen-Jye Lin, Ashley Young, Gordon S. Duncan, Hiroki Yoshida, Andrew Wakeham, Philipp A. Lang, Kiichi Murakami, Pamela Ohashi, and Tak W. Mak, which appeared in issue 4, January 25, 2011, of Proc Natl Acad Sci USA (108:1555–1560; first publish...
متن کاملDown-regulation and gene hypermethylation of the 14-3-3 gamma in uterine leiomyoma.
We demonstrated that the expression of 14-3-3 gamma was lower in uterine leiomyomas compared to the adjacent normal myometrium. Here, we show that 14-3-3 gamma promoter is methylated more in leiomyomas than myometrium. The level of 14-3-3 gamma protein in leiomyomas did not change in respect to age, size, location, or the type of leiomyoma. ER-alpha, ER-beta, and PR proteins were also higher in...
متن کامل14-3-3 Protein is Detectable in Blood Serum and Fetlock Joint Synovial Fluid of High Performance Horses
Objective: To investigate whether 14-3-3 eta protein is detectable in synovial fluid and blood serum of high performance horses and to study whether any significant correlation between this and matrix metalloproteinase 1 and 3 in horse synovial fluid. Design: Clinical study. Animals: Eleven standard breed horses (seven high performances and four controls). Procedures: Blood serum and fetlock...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2004
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6602004